Stem cells police themselves to reduce scarring
Stem cells produce a decoy protein to attenuate growth signals. Artificially regulating this pathway might help keep muscles supple in muscular dystrophy or during normal aging, researchers hope.
Stem cells produce a decoy protein to attenuate growth signals. Artificially regulating this pathway might help keep muscles supple in muscular dystrophy or during normal aging, researchers hope.
Unexpected cells have been found in the protective membranes that enclose the brain, the so called meninges. These ‘neural progenitors’ — or stem cells that differentiate into different kinds of neurons — are produced during embryonic development. These findings show that the neural progenitors found in the meninges produce new neurons after birth — highlighting the importance of meningeal tissue as well as these cells’ potential in the development of new therapies for brain damage or neurodegeneration.
Unexpected cells have been found in the protective membranes that enclose the brain, the so called meninges. These ‘neural progenitors’ — or stem cells that differentiate into different kinds of neurons — are produced during embryonic development. These findings show that the neural progenitors found in the meninges produce new neurons after birth — highlighting the importance of meningeal tissue as well as these cells’ potential in the development of new therapies for brain damage or neurodegeneration.
A major cause of pulmonary fibrosis, a mysterious and deadly disease that scars the lungs and obstructs breathing, has now been pinpointed by scientists. The disease, which has no known cure, appears to result from the failure of special lung stem cells that help airways recover from injury, the investigators report.
Scientists have developed a gel for growing miniaturized body organs that can be used in clinical diagnostics and drug development. Organoids are miniature organs that can be grown in the lab from a person’s stem cells. They can be used to model diseases, and in the future could be used to test drugs or even replace damaged tissue in patients.
Scientists can now grow 3-D models of lungs from stem cells, creating new ways to study respiratory diseases, report scientists.
As part of an international clinical trial, researchers at the Sheffield Teaching Hospital recently reported interesting developments in multiple sclerosis therapy. Using the patients’ own blood stem cells, the scientists were able to reboot their immune system, therefore preventing autoreactive immune cells from further attacks on their fragile nervous system.
UT Southwestern Medical Center researchers successfully boosted the regeneration of mature nerve cells in the spinal cords of adult mammals — an achievement that could one day translate into improved therapies for patients with spinal cord injuries.
For people with a type of jaw joint disorder that results from loss of cartilage, the only treatments available address symptoms but do not repair the damaged tissue. Now, a new study of mice suggests stem cells already present in the jaw joint could be manipulated to repair it.
Institute of Cell Biology National Academy of Sciences of Ukraine, All-Ukrainian Public Organization “Ukrainian Society of Cell Biology” inform you about:
International Symposium on Cell Biology jointly with 5th Ukrainian Congress for Cell Biology that will be held on October 2-6, 2016 in Odesa, Ukraine at the Ilya Mechnikov Odesa National University.