A phase I clinical trial is the first research monitored by the Food and Drug Administration that demonstrates the potential of regenerative therapy for hypoplastic left heart syndrome (HLHS) through collecting, processing and injecting an infant’s own stem cells directly into the heart at the time of surgery.

Researchers have discovered how regenerative capacity of intestinal epithelium declines when we age. Targeting of an enzyme that inhibits stem cell maintaining signaling rejuvenates the regenerative potential of an aged intestine. This finding may open ways to alleviate age-related gastrointestinal problems, reduce side-effects of cancer treatments, and reduce healthcare costs in the ageing society by promoting recovery.

n a world first, scientists have found a new way to direct stem cells to heart tissue. The findings could radically improve the treatment for cardiovascular disease, which causes more than a quarter of all deaths in the UK

Stem cell stimulation shows promise as a potential noninvasive stroke treatment, according to new research. If extended to humans, this technique could greatly improve patients’ quality of life.

Scientists have created natural-looking hair that grows through the skin using human induced pluripotent stem cells (iPSCs), a major scientific achievement that could revolutionize the hair growth industry.

How dormant neural stem cells in fruit flies are activated and generate new neurons is described in a new research study by Duke-NUS Medical School. The findings could potentially help people with brain injury or neuronal loss, if similar mechanisms apply in humans.

Engineered tissues and organs have been grown with various degrees of success in labs for many years. Many of them have used a scaffolding approach where cells are seeded onto biodegradable supportive structures that provide the underlying architecture of the organ or tissue desired.

Scientists have found that neural stem cells use molecules that form a complex called STRIPAK to ‘wake up’ and produce new neurons (nerve cells) and surrounding glial cells in the brain.

In ongoing research to find a treatment for acute kidney injury, scientists have further advanced a promising approach using therapeutic factors produced by stem cells by creating a more efficient delivery method that would improve tissue regeneration.