Current issues of skin aging and strategies for its correction

Home/2021, Vol. 9, No. 1/Current issues of skin aging and strategies for its correction

Cell and Organ Transplantology. 2021; 9(1):68-74.
DOI: 10.22494/cot.v9i1.124

Current issues of skin aging and strategies for its correction

Ivanishchev V.

  • D. F. Chebotarev State Institute of Gerontology of the National Academy of Medical Sciences of Ukraine, Kyiv, Ukraine

Abstract

The review analyzes current experimental and clinical data on skin aging. One of skin aging phenomena is the aging of its cells. Senescent cells produce a broad spectrum of cytokines that alter the microenvironment of tissues. The results of recent studies show that the microenvironment affects the functional activity of stem cells, which is accompanied by impairment in skin regeneration and recovery.

Keywords: skin aging; skin stem cells; senescent cells; senolytics

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Ivanishchev  V. Current issues of skin aging and strategies for its correction. Cell Organ Transpl. 2021; 9(1):68-74. doi:10.22494/cot.v9i1.124

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