Transplantation of mesenchymal stem cells for the treatment of demyelinating diseases

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Cell and Organ Transplantology. 2021; 9(1):60-65.
DOI: 10.22494/cot.v9i1.123

Transplantation of mesenchymal stem cells for the treatment of demyelinating diseases

Petriv T.1,2,3, Tatarchuk M.1, Tsymbaliuk Yu.1, Tsymbaliuk V.4

  • 1Romodanov State Institute of Neurosurgery, National Academy of Medical Sciences of Ukraine, Kyiv, Ukraine
  • 2Medical Center Hemafund LTD, Kyiv, Ukraine
  • 3QR Health Solutions, Kyiv, Ukraine
  • 4National Academy of Medical Sciences of Ukraine, Kyiv, Ukraine


Demyelinating diseases, especially multiple sclerosis (MS) is not only medical but also socio-economic issue. Unsatisfactory quality of life and high degree of disability in these patients require the implementation of the advanced treatments, such as stem cell transplantation. Numerous experimental and clinical studies are being conducted, revealing new mechanisms of the action of stem cells in demyelinating diseases. Further research is needed to understand many more aspects of clinical use.
This review is devoted to the use of regenerative cell technologies in the treatment of demyelinating diseases, the current state and prospects of the approach to the treatment of such pathology with stem cells.

Keywords: stem cells; cell transplantation; multiple sclerosis

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Petriv T, Tatarchuk M, Tsymbaliuk Yu, Tsymbaliuk V. Transplantation of mesenchymal stem cells for the treatment of demyelinating diseases. Cell Organ Transpl. 2021; 9(1):60-65. doi:10.22494/cot.v9i1.123

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